منابع مشابه
Oxymorphone Status
T is the second in a hoped-for series of Pain Medicine supplements that will deal with medications of interest to the pain medicine clinician. The first of these was in references to duloxetine [1]. The editors of Pain Medicine have decided to launch these supplements because research information about specific medications is often scattered among various journals and some early information may...
متن کاملOpioid rotation: what is the rush?
There are no two people in pain management that I can think of who have saved more lives than Drs. Webster and Fine. In their piece suggesting a new paradigm for opioid rotation [1], they add a distinctly useful clinical approach to what heretofore has been their empirical, political, and advisory efforts in this domain. Dr. Webster has worked tirelessly with his Lifetree foundation and with th...
متن کاملToward a systematic approach to opioid rotation
Patients requiring chronic opioid therapy may not respond to or tolerate the first opioid prescribed to them, necessitating rotation to another opioid. They may also require dose increases for a number of reasons, including worsening disease and increased pain. Dose escalation to restore analgesia using the primary opioid may lead to increased adverse events. In these patients, rotation to a di...
متن کاملLevorphanol: An Optimal Choice for Opioid Rotation
Levorphanol, termed “the forgotten opioid,” is a potent opioid analgesic available for the treatment of moderate to severe pain. It was first approved in 1953, and it has a wide range of ascending and descending pain pathway receptor-mediated pharmacological activities, including mu, delta, and kappa (kappa 1 and 3) opioid agonism; N-methyl-D-aspartate (NMDA) antagonism; and reuptake inhibition...
متن کاملFeasibility study of rapid opioid rotation and titration.
BACKGROUND Opioid guidelines recommend opioid rotation and switching for patients who do not achieve adequate pain relief or who experience intolerable adverse events (AEs) with their current opioid. However, specific recommendations and protocols for opioid rotation are lacking, making the practice time consuming and difficult for primary care physicians to accomplish independently or coordina...
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ژورنال
عنوان ژورنال: Pain Medicine
سال: 2009
ISSN: 1526-2375,1526-4637
DOI: 10.1111/j.1526-4637.2009.00598.x